To the content
1 . 2019

Probiotic using as a part of complex therapy of disbiotic violations at some intestinal diseases

Abstract

Diseases of intestines are among the most widespread in this connection their effective prevention and treatment represents a priority problem of practical health care. Nowadays the set of the indisputable evidence that the microbiota of intestines played a key role in pathogenesis of many diseases has been obtained.

Aim - the analysis of the available data on a role of microflora and efficiency of probiotic cultures for treatment of irritable bowel syndrome, the necrotic enterocolitis, Krone’s disease.

Based on the data, which is available in literature, the main aspects of biological properties of probiotic bacteria, first in the context of their regulating influence on inflammatory immune reaction have been discussed. The question of strain-specific effect of probiotics has been considered. The basic provisions concerning change of a fecal microbiota, prospect and difficulty of realization of this technique have been presented in the article.

Conclusion. Despite of wide use of pro- and prebiotics in clinic for treatment of diseases of digestive tract, a large number of the questions connected with selection of concrete strains for each patient, a dosage and duration of therapy for achievement of steady remission still remains.

Keywords:probiotics, microbiome of the person, intestines microbiota

For citation: Gurevich K.G., Nikonov E.L., Zaborova VA., Shelekhova TYu., Zolnikova O.Yu. Probiotic using as a part of complex therapy of disbiotic violations at some intestinal diseases. Voprosy pitaniia [Problems of Nutrition]. 2019; 88 (1): 77-84. doi: 10.24411/0042-8833-2019-10009. (in Russian)

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)

SCImago Journal & Country Rank
Scopus CiteScore
CHIEF EDITOR
CHIEF EDITOR
Viktor A. Tutelyan
Full Member of the Russian Academy of Sciences, Doctor of Medical Sciences, Professor, Scientific Director of the Federal Research Centre of Nutrition, Biotechnology and Food Safety (Moscow, Russia)

Journals of «GEOTAR-Media»