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6 . 2011

Relationship between changes in peroxide oxidation lipoide index, cоenzyme Q10 and free fatty acids by of rats depending of fatty acid component in the ration

AbstractOntogenetic peculiarities of relationship concentration of coenzyme (Ко) Q10, peroxide oxidation lipoide (POL) content, peroxidation index (PI), concentration of omega 3 and omega 6 PUFA and saturated fatty acid in blood serum and liver of rats of 1, 3, 9 and 12 months old are studied. In blood serum pronounced riverse dependence was discovered between КоQ10 concentration and POL process intensivety in rats of 3 to 6 month old, fed palm and linseed oil. Direct relationship was established between TBA-active products in liver of all animal groups and peroxidation index. Value PI can be used for evaluation of potential substrates of POL in experiments and for creation of ration with definite fatty acid composition.

Keywords:fish oil, palm and linseed oil, coenzyme Q10, rats of 1, 3, 6, 9 and 12 months

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CHIEF EDITOR
CHIEF EDITOR
Viktor A. Tutelyan
Full Member of the Russian Academy of Sciences, Doctor of Medical Sciences, Professor, Scientific Director of the Federal Research Centre of Nutrition, Biotechnology and Food Safety (Moscow, Russia)

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