The association of genetic polymorphisms with non-communicable disease among Arctic population

AbstractThe review analyzed genetic polymorphisms contribute to the development of non-communicable diseases among the inhabitants of the Arctic. It is known that the area belongs to the arctic areas of discomfort for living and employment rights. Ecological features of the Far North have contributed to the adaptation of the indigenous population to environmental conditions, which manifested itself in particular in the power features that provide a low prevalence of obesity, metabolic syndrome, type 2 diabetes and cardiovascular disease. Active development of the Arctic zone and the associated lifestyle changes in the population, including the nature of power, caused a change in the prevalence and trends of non-communicable diseases, which has its own characteristics in comparison with the ethnic groups living in more southern latitudes. These features, as follows from the results of a number of studies to be associated, including the presence of genetic polymorphisms characteristic of the population of the Arctic zone.

Keywords:obesity, metabolic syndrome, type 2 diabetes, cardiovascular disease, genetic polymorphisms