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6 . 2014

The role of the Consultative and Diagnostic Centre «Healthy Nutrition» in the diagnosis and nutritional prevention of non-communicable diseases

AbstractIn a consultative and diagnostic center «Healthy Nutrition» of Institute of Nutrition the nutritional status of 3500 patients (mean age 48,4±0,3 years) living in the Moscow region, using a system Nutritest IP-3, including genomic analysis has been examined. In the analysis of dietary intake by an average review, increased energy intake due to excess intake of the total (44,2% energy) and saturated fat (13,6%) has been shown. 30,0% of patients were overweight and 34,1% were obese. Osteopenia was detected in 31,0% of men and 25,0% women, osteoporosis – 20,9% and 30,3%, respectively. Analysis of the results of biochemical studies revealed increased cholesterol in 68,7% of patients, LDL cholesterol – at 63,9%, triglycerides – at 22,5%, glucose – at 29,4%. The frequency of the occurrence of risk alleles of genes associated with the development of obesity and type 2 diabetes mellitus was: 47,8% – for the polymorphism rs9939609 (FTO gene), 8,3% – for polymorphism rs4994 (gene ADRB3), 60,2% – for the polymorphism rs659366 (gene UCP2), 36,6% – for the rs5219 polymorphism in the gene of ATP-dependent potassium channel.

Keywords:dietary intake, nutritional status, hypercholesterolemia, hyperglycemia, bone density, gene polymorphism

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CHIEF EDITOR
CHIEF EDITOR
Viktor A. Tutelyan
Full Member of the Russian Academy of Sciences, Doctor of Medical Sciences, Professor, Scientific Director of the Federal Research Centre of Nutrition, Biotechnology and Food Safety (Moscow, Russia)

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