Gastroesophageal reflux disease: the role of nutritional patterns in pathogenesis and treatment
AbstractGERD is a common gastrointestinal disorder which has a great impact on patient’s quality of life. Despite of the fact that this disease depends on patient’s diet there is no evidence-based recommendations for patients experiencing GERD symptoms. The aim of the study was to evaluate the impact of diet on disease’s manifestations and progression. Systematic review in PubMed/Medline databases was performed with keywords food, dietary patterns, nutrients, nutrition, fat, proteins, carbohydrates, beverages, salt, fiber в комбинации с gastroesophageal reflux, GERD. 197 publications were found, 54 selected according to the following criteria: the article should contain data of clinical observations, or to be a meta-analysis; group characteristics, study design, and results be available for the analysis. The review contains data concerning influence of protein, fat, carbohydrate intake, some beverages and carminatives on clinical manifestations of GERD. The literature data about impact of diet on the manifestations of GERD are controversial, that makes impossible to produce the evidence-based recommendations concerning diet modifications for GERD patients. There is a need for prospective studies evaluating correction of diet on the course of the disease.
Keywords:gastroesophageal reflux disease, GERD, diet, protein, fats, carbohydrates, spices, coffee, carbonateddrinks, alcohol